Endocrine Diseases

Cushing's Syndrome


Cushing's syndrome, also known as hyperadrenocorticism, is a condition characterized by an increase in glucocorticoids secreted by the adrenal glands. About 85 percent of cases are caused by a tumor in the pituitary gland, while 15 percent are caused by an adrenal tumor. The pituitary gland produces a hormone that signals the adrenal gland to produce cortisol; a tumor can cause it to produce the adrenal-stimulating hormone even when it is not needed.


Diabetes Mellitus


Diabetes Mellitus in dogs is type 1, or insulin dependent diabetes: a lack of insulin production due to destruction of pancreatic beta cells. Current research indicates no evidence of type 2 diabetes in dogs. Among the causes of diabetes mellitus in dogs are autoimmune disease or severe pancreatitis. Forms of diabetes which may not be permanent, depending on the amount of damage to the beta cells of the endocrine pancreas, are transient and secondary diabetes.




Hyperthyroidism is rare in dogs. The most common cause is thyroid carcinoma, a malignant tumor. Signs include weight loss, increased appetite, and enlargement of the thyroid gland.


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